Chapter 14 Infection, Infectious Disease, and Epidemiology

I. Epidemiologic terminology – Define these terms from your book

A.     Communicable disease -

B.     Portal of entry

C.     Reservoir

D.     Mortality Rate

E.      Morbidity Rate

F.      Incidence

G.     Endemic

H.     Pandemic

I.        Pathogenic, Pathogenesis

J.       Symptomatic vs Asymptomatic

K.    Vector

L.      Virulence

II. Relationships Between Microbes and their Hosts 

A.     Symbiosis

1.      Mutualism

2.      Commensalism

3.      Parasitism

B.     Normal Flora

1.      Acquiring Normal Flora

2.      Opportunistic Pathogens

3.      Portals of Entry – Give examples of diseases using these as the main portal of entry

a.       Contact – Skin

b.      Indirect Contact – Exposure to an inanimate object carrying a pathogen

c.       Air or Droplet Transmission - Mucous Membranes

d.      Food and Waterborne -

e.       STD - Mucous Membranes

f.      Parenteral

g.   Transplacental

 

4.      Adhesion and virulence factors

 

III. Characteristics of Infections

A.     Signs

B.     Symptoms

C.     Syndromes

D.     Etiology

1.      Koch’s Postulates

2.      Exceptions to Koch’s Postulates

E.      Virulence Factors

a.       Enzymes

b.      Toxins

c.       Inhibition of Phagocytosis

 

F.      Stages of Infectious Diseases

        G. Signs and Symptoms

IV. Transmission of Infectious Disease

A.     Contact

B.     Indirect or Vehicle

C.     Vector

V. Epidemiology

A.     What is it?

B.     What does it tell us?

VI. Nosocomial Infections

A. Other patients

B. Healthcare workers

C. Endogenous

D. Medical Devices

E. Airborne

F. Invasive procedures

 

Chapter 14 Disease, Infectious Disease, and Epidemiology

1. Define common terms related to infectious diseases.

2. Describe the concept of normal flora, indicate common normal flora by name and location on the body.

3. Identify the parts of the body which are normally sterile.

4. Discuss the transmission routes for infectious disease.

5. Compare and contrast communicable and non-communicable disease, endemic and epidemic disease, acute and chronic disease, primary and secondary disease, and local and systemic disease

6. Explain the meaning of portal of entry, dose, and tissue penetration as they relate to the establishment of disease.

7. Compare exotoxins and endotoxins, specifying the source, chemical composition, effects, and examples of organisms producing them.

8. Define terminology typically used with epidemiology.

9. Evaluate how portals of entry influence the epidemiology of diseases using examples.

10. Illustrate epidemiologic principles common to emerging infections.

11. Discuss the significance of nosocomial infections and contrast their control with community acquired infections.

 

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